Central precocious puberty due to hypothalamic hamartoma in neurofibromatosis type 1.
نویسندگان
چکیده
1Neurology Unit and Laboratories, Anna Meyer Children’s University Hospital, Florence; 2Stella Maris Foundation, Calambrone, Pisa; 3Health Sciences Department, University of Florence, Anna Meyer Children’s University Hospital, Florence; 4Quantitative and Functional Neuroradiology Research Program at Anna Meyer Children’s and Careggi University Hospitals, University of Florence, Florence; 5Medical Physics Unit at Anna Meyer Children’s University Hospital, Florence; Italy HORMONES 2016, 15(1):144-146
منابع مشابه
Central precocious puberty secondary to hypothalamic hamartoma
Introduction Central precocious puberty (CPP) presenting at a very young age is likely to have an underlying pathology. One of the pathologies is hypothalamic hamartoma (HH), a non-neoplastic tumour-like lesion located at the floor of the third ventricle, near the tuber cinereum. Two young children with CPP due to HH without gelastic seizures or mental retardation were successfully managed and ...
متن کاملA case of precocious puberty in a setting with limited resources.
Precocious puberty is a rare condition characterized by the development of secondary sexual characteristics before the median age for the sex. It is either gonadotropin dependent also called as central or gonadotropin independent also known as peripheral type. Hypothalamamic Hamartoma is a common cause of the central or precocious puberty due to organic brain lesion. Here we present a two year ...
متن کاملCentral Precocious Puberty due to Hypothalamic Hamartomas Correlates with Anatomic Features but Not with Expression of GnRH, TGF, or KISS1
Background/Aims: Hypothalamic hamartomas are the most common identifiable cause of central precocious puberty (CPP). Hamartoma characteristics proposed to be associated with CPP include specific anatomic features and expression of molecules such as gonadotropin-releasing hormone (GnRH), transforming growth factor (TGF ), and GRM1A , which encodes the type 1 metabotropic glutamate receptor isofo...
متن کاملWhether all patients with Central precocious puberty should be treated?
Extended Abstract Precocious puberty is the appearance of secondary sexual characteristics before 8 years old in girls and 9 years old in boys. Precocious puberty is divided into 3 groups of central, peripheral and normal variants. Central precocious puberty is accompanied by activation of hypothalamic-pituitary-gonadal axis which causes increase in secretion of GnRH, and in turn increase i...
متن کاملCentral precocious puberty due to hypothalamic hamartomas correlates with anatomic features but not with expression of GnRH, TGFalpha, or KISS1.
BACKGROUND/AIMS Hypothalamic hamartomas are the most common identifiable cause of central precocious puberty (CPP). Hamartoma characteristics proposed to be associated with CPP include specific anatomic features and expression of molecules such as gonadotropin-releasing hormone (GnRH), transforming growth factor alpha (TGFalpha), and GRM1A, which encodes the type 1 metabotropic glutamate recept...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Hormones
دوره 15 1 شماره
صفحات -
تاریخ انتشار 2016